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When teaching data mining, we like to illustrate rather than only explain. And Orange is great at that. Long-Acting Liminoids in Citrus Add to Their Ability to Promote Optimal Health In animal studies and laboratory tests with human cells, compounds in citrus fruits, including oranges, called limonoids have been shown to help fight cancers of the mouth, skin, lung, breast, stomach and colon.

Now, scientists from the US Agricultural Research Service have shown that our bodies can readily absorb and utilize a very long-acting limonoid called limonin that is present is citrus fruits in about the same amount as vitamin C. In citrus fruits, limonin is present in the form of limonin glucoside, in which limonin is attached to a sugar glucose molecule.

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Our bodies easily digest this compound, cleaving off the sugar and releasing limonin. In the ARS study, 16 volunteers were given a dose of limonin glucoside in amounts ranging from those that would be found in from 1 to 7 glasses of orange juice.

Blood tests showed that limonin was present in the plasma of all except one of the subjects, with concentrations highest within 6 hours after consumption. Traces of limonin were still present in 5 of the volunteers 24 hours after consumption!

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Limonin's bioavailability and persistence may help explain why citrus limonoids are potent anti-carcinogens that may continuously prevent cancerous cells from proliferating. Other natural anti-carcinogens are available for much less time; for example, the phenols in green tea and chocolate remain active in the body for just 4 to 6 hours. Lab tests indicate that human liver cells produce less apo B when exposed to limonin.

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Apo B is a structural protein that is part of the LDL cholesterol molecule and is needed for LDL production, transport and binding, so higher levels of apo B translate to higher levels of LDL cholesterol. Compounds in Orange Peel May Lower Cholesterol as Effectively as Statin Drugs A class of compounds found in citrus fruit peels called polymethoxylated flavones PMFs have the potential to lower cholesterol more effectively than some prescription drugs, and without side effects, according to a study by U.

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Treatment with PMFs did not appear to have any effect on levels of beneficial HDL cholesterol, and no negative side effects were seen in the animals fed the PMF-containing diets. Although a variety of citrus fruits contain PMFs, the most common PMFs, tangeretin and nobiletin, are found in the peels of tangerines and oranges.

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Juices of these fruits also contain PMFs, but in much smaller amounts. In fact, you'd have to drink about 20 glasses of juice each day to receive an amount of PMFs comparable in humans to that given to the animals. However, grating a tablespoon or so of the peel from a well-scrubbed organic tangerine or orange each day and using it to flavor tea, salads, salad dressings, yogurt, soups, or hot oatmeal, buckwheat or rice may be a practical way of achieving some cholesterol-lowering benefits. The researchers are currently exploring the mechanism of action by which PMFs lower cholesterol.

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Based on early results in cell and animal studies, they suspect that PMFs work like statin drugs, by inhibiting the synthesis of cholesterol and triglycerides inside the liver. Oranges Possible Prevention of Kidney Stones Want to reduce your risk of calcium oxalate kidney stones?

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All the informations about the Group: press releases, news, investors, shareholders, consolidated results, candidate, innovations, networks, corporate social. Orange usually refers to: Orange (colour), occurs between red and yellow in the visible spectrum; Orange (fruit), the fruit of the tree species Citrus × sinensis.

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